Viral vectors expressing proneural genes can stimulate adult mammalian retinal glia to become immature neurons. These glia-derived neurons share properties with the bipolar, amacrine and retinal ...

In the randomized, sham-controlled ARTEMIS study, patients will receive either a dose of ixo-vec or a standard care regimen of anti-VEGF Eylea.

Several of these therapeutics use vectors derived from adeno-associated viruses (AAV) as a delivery mechanism to inhibit the expression of VEGF. However, they are in various stages of development.

Adverum Biotechnologies, Inc. (Nasdaq: NASDAQ:ADVM), a clinical-stage company that aims to establish gene therapy as a new standard of care for highly prevalent ...

Yet many more applications await. One of the most actively investigated gene transfer vehicles and emerging platforms is that of adeno-associated virus (AAV). Simply put, AAV consists of a protein ...