BMJ13h
Proximity extension assay testing reveals novel diagnostic biomarkers of atypical parkinsonian syndromes
Objective The high degree of clinical overlap between atypical parkinsonian syndromes (APS) and Parkinson’s disease (PD) makes diagnosis challenging. We aimed to identify novel diagnostic protein ...
BMJ13d
The nosological position of apathy in clinical practice
Apathy is increasingly recognised as a common behavioural syndrome in psychiatric disorders, but it is conceptually ill defined. The aim of this study was to examine the concept of apathy as it is ...
BMJ5d
Occurrence and risk factors for apathy in Parkinson disease: a 4-year prospective longitudinal study
Correspondence to Dr K F Pedersen, The Norwegian Centre for Movement Disorders, Stavanger University Hospital, PO Box 8100, N-4068 Stavanger, Norway; kenfrp{at}online.no Background: Apathy is a common ...
BMJ5d
Association of autonomic symptoms with disease progression and survival in progressive supranuclear palsy
Background Development of autonomic failure is associated with more rapid disease course and shorter survival in patients with Parkinson’s disease and multiple system atrophy. However, autonomic ...
BMJ5d
Normal pressure hydrocephalus: long-term outcome after shunt surgery
Background/objective: Little is known about the long-term clinical course and management of patients with normal pressure hydrocephalus (NPH) treated by cerebrospinal fluid (CSF) shunting. Methods: We ...
BMJ5d
The spectrum of neuropsychiatric symptoms in patients with early untreated Parkinson’s disease
The Norwegian Centre for Movement Disorders, Stavanger University Hospital, Stavanger, Norway Background: Neuropsychiatric symptoms are common in Parkinson’s disease (PD) and have important clinical ...
BMJ6d
Low vitamin B-12 status in confirmed Alzheimer’s disease as revealed by serum holotranscobalamin
2 Oxford Project to Investigate Memory and Aging (OPTIMA), Department of Pharmacology, University of Oxford Correspondence to: Professor A David Smith, University Department of Pharmacology, Mansfield ...
BMJ7d
Which neuropsychiatric and behavioural features distinguish frontal and temporal variants of frontotemporal dementia from Alzheimer's disease?
OBJECTIVES To investigate the prevalence of changes in mood, personality, and behaviour in frontotemporal dementia (FTD) and Alzheimer's disease (AD) and hence, which features reliably distinguish ...
BMJ10d
Cognitive presentation of multiple sclerosis: evidence for a cortical variant
Background: Although neuropsychiatric complications are well recognised, the presentation of multiple sclerosis with cognitive or neuropsychiatric symptoms has generally been considered a rare ...
BMJ5d
Expanding the phenotype of MOG antibody-associated disease (MOGAD): half a century of epilepsy and relapsing optic neuritis
Correspondence to Dr Axel Petzold, UCLH NHNN, UCL ION, Queen Square, Moorfields Eye Hospital City Road Campus, London WC1E 6BT, UK; a.petzold{at}ucl.ac.uk The 69-year-old woman with relapsing ON ...
BMJ11d
Acquired hepatocerebral degeneration: full recovery after liver transplantation
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