But he wasn’t about to let mitochondrial disease Leber’s hereditary optic neuropathy (LHON) stand in his way, and he made his first appearance as part of Italy’s Paralympic team in 2016 ...

Since being diagnosed with the rare optic nerve disorder, Leber's hereditary optic neuropathy (LHON), she has become a published poet and author. And through her patient advocacy work, Paula has ...

Leber's hereditary optic neuropathy (LHON) is a maternally inherited mitochondrial condition that manifests as painless subacute bilateral visual loss usually in early adulthood. It is caused by DNA ...

A multinational study led by the LHON Study Group has revealed sustained visual improvements and a favorable safety profile five years following lenadogene nolparvovec gene therapy in patients ...

A large international study conducted by the LHON Study Group reported that a unilaterally administered gene therapy to treat Leber hereditary optic neuropathy (LHON) caused by the MT-ND4 gene variant ...

Lenadogene nolparvovec gene therapy showed sustained bilateral visual acuity improvement in LHON patients with the MT-ND4 gene variant over five years. The RESTORE study confirmed the therapy's ...

“The findings on the persistence of visual improvement show the promise of using LUMEVOQ gene therapy to treat patients with LHON due to the MT-ND4 gene variant,” noted Prof. Patrick Yu-Wai ...