A genome search and protein language model produced new DNA-moving proteins, including one that doubled targeted insertion in ...
A virus-built molecular weapon targets DNA with a strange gapped code and may reveal how bacteria acquired the foundations of ...
Scientists have long believed that large stretches of our genetic material, known as long noncoding RNAs (lncRNAs), help regulate genes but do not produce proteins. A new study by Stav Zok and ...
Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...
Most biochemistry labs that study DNA isolate it within a water-based solution that allows scientists to manipulate DNA without interacting with other molecules. They also tend to use heat to separate ...
Determining protein structures requires crystals, but getting proteins to crystallize has long depended on a slow, unpredictable process of trial and error ...
DNA can be damaged by normal cellular processes as well as external factors such as UV radiation and chemicals. Such damage can lead to breaks in the DNA strand. If DNA damage is not properly repaired ...
So, if we modify proteins with DNA and assemble them, we can form high-quality, atomically precise crystals, overcoming a decades-old challenge in the field of DNA-programmable assembly." Discover the ...
T, is one of the most devastating genome-instability disorders known to medicine. Children born with the condition face ...
Replication Protein A (RPA) is the principal single-stranded DNA (ssDNA)-binding complex in eukaryotic cells, orchestrating fundamental processes of DNA replication, repair and recombination. As a ...
Scientists have captured the most detailed structural images to date of a specific type of protein's DNA repair process, a finding that could reveal ways to inhibit the effects of BRCA1 and BRCA2 ...