Not suiting up Sunday is safety Talanoa Hufanga who rolled his ankle in practice Thursday. Hufanga returned in Week 3 after recovering from a torn ACL in Week 11 last season. It’s unclear whether rookie Malik Mustapha or veteran George Odum will start in his stead.

Deebo Samuel was projected miss multiple weeks with a calf injury that forced him out of the San Francisco 49ers game in Week 3 against the Los Angeles Rams. But now, it’s looking like a possibility that he’ll play in Week 4 against the New England Patriots after limited practices on Thursday and Friday.

The 49ers are shorthanded on offense, but could be getting a key contributor back in Week 4. Blaine Grisak breaks down what Deebo Samuel’s status means for fantasy football.